![Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4 Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4](https://www.frontiersin.org/files/Articles/600000/fimmu-11-600000-HTML-r1/image_m/fimmu-11-600000-g003.jpg)
Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4
![This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced](https://www.cytoskeleton.com/media/Feb_14_CS_image_2.gif)
This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced
![3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram 3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram](https://www.researchgate.net/publication/274386360/figure/fig2/AS:978234644631553@1610240722589/CD80-and-CD86-deliver-bidirectional-signaling-for-the-activation-of-T-cell-and-APC.png)
3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram
![CD86 signaling model. Dotted arrows indicate proposed novel signaling... | Download Scientific Diagram CD86 signaling model. Dotted arrows indicate proposed novel signaling... | Download Scientific Diagram](https://www.researchgate.net/publication/233930359/figure/fig7/AS:385221229858818@1468855306675/CD86-signaling-model-Dotted-arrows-indicate-proposed-novel-signaling-events-identified.png)
CD86 signaling model. Dotted arrows indicate proposed novel signaling... | Download Scientific Diagram
![Comité Départemental de Tennis de Table de la Vienne – Site officiel du Comité de la Vienne de Tennis de Table Comité Départemental de Tennis de Table de la Vienne – Site officiel du Comité de la Vienne de Tennis de Table](https://cd86tt.fr/wp-content/uploads/2022/05/bandeau_siteweb_essai1.png)
Comité Départemental de Tennis de Table de la Vienne – Site officiel du Comité de la Vienne de Tennis de Table
![2 CD80/CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram 2 CD80/CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram](https://www.researchgate.net/publication/274386280/figure/fig2/AS:978234418151425@1610240668507/CD80-CD86-deliver-bidirectional-signaling-for-the-activation-of-T-cell-and-APC-Cognate.jpg)
2 CD80/CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram
![Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13073-020-00756-z/MediaObjects/13073_2020_756_Fig5_HTML.png)